A Case of Multiple Epidermolytic Acanthoma of the Scrotum: Is the Human Papillomavirus a Culprit?

Vol. 27, No. 5, 2015 633 Received October 8, 2014, Revised December 9, 2014, Accepted for publication December 15, 2014 Corresponding author: Mi Woo Lee, Department of Dermatology, Asan Medical Center, 88 Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea. Tel: 82-2-3010-3460, Fax: 82-2-486-7831, E-mail: miumiu@amc. seoul.kr This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Fig. 2. Compact hyperkeratosis with acanthosis. Perinuclear vacuolization, of variable size, of the keratinocytes in the stratum spinosum and stratum granulosum. The keratinocytes exhibited non-well-defined limits that gave the epidermis a reticulate appearance. Hypergranulosis with coarse keratohyalin granules was also observed (H&E, ×200). Fig. 1. Multiple well-demarcated <5 mm gray to whitish round papules on the scrotum. http://dx.doi.org/10.5021/ad.2015.27.5.633